Could a pill slow language loss in rare dementia?
NCT ID NCT05184569
First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 28 times
Summary
This early-stage study tests whether an oral drug called Verdiperstat is safe and tolerable for people with semantic variant primary progressive aphasia (svPPA), a rare dementia that gradually destroys the ability to understand words and recognize objects. About 64 adults with svPPA will take either the drug or a placebo twice daily for 24 weeks. The main goal is to check for side effects, while also measuring how the drug behaves in the body and its potential effects on symptoms.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
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Locations
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Houston Methodist Hospital - Nantz National Alzheimer Center
RECRUITINGHouston, Texas, 77030, United States
Contact
Contact
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Mayo Clinic
RECRUITINGRochester, Minnesota, 55905, United States
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Northwestern University
RECRUITINGChicago, Illinois, 60611, United States
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UCSF Memory and Aging Center
RECRUITINGSan Francisco, California, 94158, United States
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University of Pennsylvania
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Conditions
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