Heart risk under the microscope: verapamil for cluster headaches
NCT ID NCT04406259
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at how often a common heart side effect (first-degree atrioventricular block) occurs when verapamil is used at high doses to prevent cluster headaches. Researchers will monitor 60 patients starting or already on verapamil, using ECGs and blood tests. The goal is to better understand and track these heart conduction issues, not to test if verapamil works.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Verapamil
What this could lead to
If successful, this could help doctors better understand and manage the heart-related side effects of high-dose verapamil when used for cluster headache prevention.
What could go wrong
This is a small, observational study focused on side effects, not on whether verapamil works for headaches. It may not lead to new treatments or change current practice.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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AP-HP Hôpital la Timone
Marseille, 13005, France
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CHU de Nice
Nice, CHUN, 06003, France