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Gentle lung breathing during bypass may prevent Post-Surgery collapse

NCT ID NCT02070445

Terminated Knowledge-focused Sponsor: McMaster University Source: ClinicalTrials.gov ↗

First seen Jul 10, 2026 · Last updated Jul 10, 2026

Summary

This pilot study tests whether keeping the lungs gently ventilated during cardiopulmonary bypass (heart-lung machine) reduces lung collapse after heart surgery. Adults having elective coronary artery bypass surgery will be randomly assigned to receive ventilation or not during bypass. Lung ultrasound scans will measure collapse at several time points before and after surgery. The study also looks at infection rates, time on the breathing tube, hospital stay length, and blood oxygen levels.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
mechanical ventilation during cardiopulmonary bypass
What this could lead to
If keeping the lungs ventilated during bypass reduces lung collapse, it could lead to faster recovery and fewer lung complications after heart surgery.
What could go wrong
This is a small pilot study focused on feasibility, not proof of benefit. The approach may not show a meaningful difference or may not be practical in busy surgical settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

coronary artery disorder middle lobe syndrome Pulmonary Atelectasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PULMONARY ATELECTASIS

Contacts and locations

Locations

  • Hamilton General Hospital

    Hamilton, Ontario, L8L 2X2, Canada

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