Can stretching leg veins raise blood pressure? new study investigates

NCT ID NCT03496792

Recruiting now Knowledge-focused Sponsor: Milton S. Hershey Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 10, 2026 · Updated 2 times

Summary

This study looks at whether stretching the veins in your legs causes a rise in blood pressure when you stand up, a condition called orthostatic hypertension. Researchers will use a tilt table and inflatable trousers to gently stretch leg veins in 30 healthy adults and people with high standing blood pressure. They will measure nerve activity and blood pressure to understand the body's reflex response.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help explain why some people's blood pressure rises when they stand, pointing toward better treatments for orthostatic hypertension.
What could go wrong: This is a small, early-stage observational study with only 30 participants, so results may not apply broadly. It measures nerve activity and blood pressure, not a treatment, so direct patient benefits are far off.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

essential hypertension hypertensive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BLOOD PRESSURE

Contacts and locations

Locations

Penn State Milton S. Hershey Medical Center
RECRUITING

Hershey, Pennsylvania, 17033, United States

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