Kidney drug trial halted: no benefit seen in ADPKD patients

NCT ID NCT04705051

First seen Nov 01, 2025 · Last updated May 21, 2026 · Updated 29 times

Summary

This study looked at whether starting venglustat early could slow kidney growth in people with a fast-progressing form of polycystic kidney disease (ADPKD). It enrolled 24 adults who had already completed a previous venglustat study. The trial was stopped early because the drug did not show enough benefit, though no major safety issues were found.

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Contacts and locations

Locations

  • Investigational Site Number :0360001

    Westmead, New South Wales, 2145, Australia

  • Investigational Site Number :0560002

    Leuven, 3000, Belgium

  • Investigational Site Number :2760001

    Berlin, 10117, Germany

  • Investigational Site Number :3920001

    Sapporo, Hokkaido, 060-8648, Japan

  • Investigational Site Number :3920002

    Bunkyo-ku, Tokyo, 113-8431, Japan

  • Investigational Site Number :3920004

    Shinjuku-ku, Tokyo, 162-8666, Japan

  • Investigational Site Number :3920007

    Osaka, Osaka, 545-8586, Japan

  • Investigational Site Number :4100002

    Seoul, Seoul-teukbyeolsi, 07061, South Korea

  • Investigational Site Number :5280002

    Nijmegen, 6525GA, Netherlands

  • Investigational Site Number :7240003

    Barcelona, Barcelona [Barcelona], 08003, Spain

  • Investigational Site Number :8400019

    Morgantown, West Virginia, 26506-9180, United States

Conditions

Explore the condition pages connected to this study.