Could a targeted pill boost transplant success in older blood cancer patients?
NCT ID NCT07396480
First seen Feb 09, 2026 · Last updated May 16, 2026 · Updated 8 times
Summary
This phase 3 trial compares two conditioning regimens before stem cell transplant in adults over 50 with acute myeloid leukemia or myelodysplastic syndrome. One group gets standard chemotherapy (fludarabine + melphalan), the other adds venetoclax, a targeted pill. The goal is to see if adding venetoclax improves survival without severe graft-versus-host disease. About 186 participants will be enrolled.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Jiangsu Province Hospital (The First Affiliated Hospital of Nanjing Medical University)
RECRUITINGNanjing, Jiangsu, China
Contact Email: •••••@•••••
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Nanfang Hospital Southern Medical University
RECRUITINGGuangzhou, Guangdong, China
Contact
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Qilu Hospital of Shandong University
RECRUITINGJinan, Shandong, China
Contact
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Second Affiliated Hospital of Army Medical University (Xinqiao Hospital)
RECRUITINGChongqing, China
Contact Email: •••••@•••••
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Shanghai General Hospital (Shanghai First People's Hospital)
RECRUITINGShanghai, China
Contact
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Sir Run Run Shaw Hospital Zhejiang University School of Medicine
RECRUITINGHangzhou, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The Affiliated People's Hospital of Ningbo University
RECRUITINGNingbo, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The First Affiliated Hospital of Fujian Medical University
RECRUITINGFuzhou, Fujian, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The First Affiliated Hospital of Ningbo University
RECRUITINGNingbo, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The First Affiliated Hospital of Wenzhou Medical University
RECRUITINGWenzhou, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Traditional Chinese Medicine)
RECRUITINGHangzhou, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The First Affiliated Hospital of Zhengzhou University
RECRUITINGZhengzhou, Henan, China
Contact Email: •••••@•••••
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The Second Affiliated Hospital, Zhejiang University School of Medicine
RECRUITINGHangzhou, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
RECRUITINGWuhan, Hubei, China
Contact
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Xiangya Hospital Central South University
RECRUITINGChangsha, Hunan, China
Contact Email: •••••@•••••
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Zhejiang Cancer Hospital & Hangzhou Institute of Medicine, Chinese Academy of Sciences
RECRUITINGHangzhou, Zhejiang, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Zhejiang Provincial Peoples's Hospital
RECRUITINGHangzhou, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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the First Affiliated Hospital, Zhejiang University School of Medicine
RECRUITINGHangzhou, Zhejiang, 311121, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
Explore the condition pages connected to this study.