Can a Life-Saving transplant leave hidden scars on a Child's mind?
NCT ID NCT07766304
First seen Aug 14, 2026 · Last updated Aug 14, 2026
Summary
This study looks at children aged 6 to 8 who had a stem cell transplant at least two years ago to treat a primary immunodeficiency—a genetic condition that weakens the immune system. Researchers will use standardized tests and interviews to measure the children's thinking skills, attention, memory, and emotional well-being, as well as how they function socially. The goal is to understand the long-term psychological and cognitive effects of this demanding treatment, which are not well known in this specific group of children.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Allogeneic hematopoietic stem cell transplantation (a procedure where a child receives healthy stem cells from a donor to rebuild their immune system)
- What this could lead to
- If successful, this could reveal how stem cell transplants affect children's thinking, emotions, and social life years later, guiding better support and follow-up care.
- What could go wrong
- This is a small pilot study with only 30 children, so findings may not apply to all. It observes outcomes but does not test a new treatment, so it cannot change how transplants are done directly.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Hôpital Necker-Enfants Malades
Paris, 75015, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a Low-Dose antifungal shield vulnerable patients from deadly fungal infections?
- Could a simple drug infusion stop a dangerous virus after stem cell transplants?
- Study to reveal if younger donors boost transplant success
- Can donor t cells beat a tough virus after transplant? new trial aims to find out.
- Ancient heat therapy tested for Life-Threatening transplant complication
- Food bags for transplant patients: a recipe for better recovery?