Simple urine test may forecast brain cancer recurrence

NCT ID NCT00083512

First seen Jun 27, 2026 · Last updated Aug 12, 2026 · Updated 6 times

Summary

This study collects blood and urine samples from 200 adults with glioblastoma (a type of brain tumor) who are receiving radiation therapy. Researchers want to see if levels of two proteins, VEGF and MMP, can predict whether the tumor will come back within one year. The goal is to develop a simple test to guide future treatment decisions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could lead to a simple urine or blood test to predict whether a glioblastoma will come back within a year after radiation.
What could go wrong
This is an observational study, not a treatment trial. It may not find a clear link between these proteins and recurrence, and results may not change patient care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

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