New drug combo targets Hard-to-Treat lung cancer

NCT ID NCT07549061

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 2 trial tests a new drug called vebreltinib combined with standard chemotherapy as a first treatment for people with advanced non-small cell lung cancer that has MET overexpression and no other known genetic drivers. The study will enroll 19 participants to see if the combination shrinks tumors and controls the disease. It aims to find a better option for this specific group of lung cancer patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Vebreltinib (a targeted drug) combined with platinum-based chemotherapy

What this could lead to

If successful, this could offer a new first-line treatment option for people with a specific type of advanced lung cancer that has MET overexpression.

What could go wrong

This is a small, early-phase trial with only 19 participants, so results may not apply to everyone. The drug combination may cause side effects or not work better than standard chemo.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

lung neoplasm non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • 241 West Huaihai Road, Xuhui District, Shanghai, 200030, China.

    Shanghai, Shanghai Municipality, China