Gut bacteria joins fight against advanced cancer
NCT ID NCT04208958
Summary
This early-stage study tested whether adding a new investigational therapy called VE800—a preparation of specific bacteria—could improve the effectiveness of an existing immunotherapy drug (nivolumab) in patients with advanced or metastatic cancers. The trial enrolled 56 patients with melanoma, stomach, or colorectal cancer to primarily check the safety of the combination and see if it helped shrink tumors. Researchers wanted to see if the bacteria could boost the body's immune system to better attack the cancer.
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Contacts and locations
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Locations
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Baylor Scott and White Center for Advanced Heart and Lung Disese
Dallas, Texas, 75246, United States
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Florida Cancer Specialists
Sarasota, Florida, 34232, United States
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HonorHealth Research Institute
Scottsdale, Arizona, 85258, United States
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Huntsman Cancer Institute and Hospital
Salt Lake City, Utah, 84112, United States
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Indiana University Melvin and Bren Simon Cancer Center
Indianapolis, Indiana, 46202, United States
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John Theurer Cancer Center
Hackensack, New Jersey, 07601, United States
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Moffitt Cancer Center
Tampa, Florida, 33612, United States
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New York University Medical Oncology Associates
New York, New York, 10016, United States
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Pacific Hematology Oncology Associates
San Francisco, California, 94115, United States
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Swedish Medical Oncology - First Hill
Seattle, Washington, 98104, United States
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The Angeles Clinic and Research Institute - West Los Angeles Office
Santa Monica, California, 90404, United States
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The Miriam Hospital
Providence, Rhode Island, 02906, United States
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The University of Chicago
Chicago, Illinois, 60637, United States
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UPMC Hillman Cancer Center
Pittsburgh, Pennsylvania, 15232, United States
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University of California Los Angeles
Los Angeles, California, 90095, United States
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University of California Los Angeles
Santa Monica, California, 90404, United States
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Washington University School of Medicine Siteman Cancer Center
St Louis, Missouri, 63110, United States
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Weill Cornell Medicine
New York, New York, 10065, United States
Conditions
Explore the condition pages connected to this study.