New formula could prevent dangerous clotting in dialysis machines

NCT ID NCT07293936

Recruiting now Knowledge-focused Sponsor: Gwyndolyn M. Radford Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a simple math formula can accurately predict when blood filters will clog during continuous kidney dialysis (CRRT). Filter clotting is a common problem that causes blood loss and reduces treatment effectiveness. Researchers will compare the formula's predictions against actual blood samples from 20 adult patients on CRRT. If the formula proves accurate, it could help doctors adjust dialysis settings in real time to prevent clotting, improving safety and lowering costs.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If the formula works, it could give doctors a simple, low-cost way to predict and prevent filter clotting during dialysis, improving patient safety and reducing costs.
What could go wrong: This is a very small, early validation study with only 20 participants. The formula may not prove accurate enough for real-world use, and results may not apply to all patients or settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

kidney failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CONTINUOUS RENAL REPLACEMENT THERAPY HEMOFILTER CLOTTING RENAL FAILURE

Contacts and locations

Locations

University of Iowa Hospitals and Clinics
RECRUITING

Iowa City, Iowa, 52242, United States

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