New combo aims to shrink Hard-to-Treat breast cancer

NCT ID NCT05633979

First seen Jan 22, 2026 · Last updated Apr 29, 2026 · Updated 13 times

Summary

This early-phase study tests a new drug (valemetostat) combined with a targeted therapy (trastuzumab deruxtecan) in people with HER2 low, ultra-low, or null metastatic breast cancer. The main goal is to find a safe dose and see if the combination can shrink tumors. About 17 adults with this type of breast cancer that has spread will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.