New pill may boost botox for stubborn neck spasms

NCT ID NCT06771323

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This Phase 2 trial tests whether adding valbenazine (a daily pill) to standard botox injections can further reduce neck muscle spasms and pain in people with cervical dystonia. About 20 adults who still have symptoms despite botox will receive either valbenazine or a placebo for 12 weeks. The study measures changes in a severity scale for neck dystonia.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
valbenazine
What this could lead to
If it works, this could point toward a new oral add-on treatment to improve motor symptoms in people with cervical dystonia who still have symptoms after botox injections.
What could go wrong
This is a small, early Phase 2 trial with only 20 participants, so results may not apply to everyone. The drug may not provide meaningful benefit or could cause side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Virginia Commonwealth University

    RECRUITING

    Richmond, Virginia, 23298, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.