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Sound waves aimed at the brain could ease twisted neck

NCT ID NCT07690514

Recruiting now Symptom relief Sponsor: Robert Chen Source: ClinicalTrials.gov ↗

First seen Jul 08, 2026 · Last updated Jul 09, 2026 · Updated 1 time

Summary

This study tests whether low-intensity focused ultrasound (LIFUS) can reduce symptoms of cervical dystonia, a condition causing painful neck muscle spasms. Researchers will compare two brain targets (globus pallidus and dentate nucleus) against a sham procedure in 48 adults. Participants attend seven visits over about two weeks, with assessments including symptom scales and brain scans.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Low-intensity focused ultrasound (LIFUS) to the globus pallidus or dentate nucleus
What this could lead to
If it works, this could offer a non-invasive, drug-free option to reduce neck twisting and pain in cervical dystonia.
What could go wrong
This is an early, small study (48 people) testing a new approach. It may not work better than placebo, and effects may be temporary.

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Conditions

The condition(s) this trial relates to.

cervical dystonia Torticollis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CERVICAL DYSTONIA

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Toronto Western Hospital

    RECRUITING

    Toronto, Ontario, M5T 2S8, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

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