Ear stimulation may help repair nerve damage in multiple sclerosis
NCT ID NCT06641271
First seen Jul 06, 2026 · Last updated Jul 07, 2026 · Updated 1 time
Summary
This study tests whether stimulating the vagus nerve through the ear, while doing a hand coordination task, can improve motor function in people with multiple sclerosis. Participants will receive either active or sham stimulation during 30-minute sessions over a month, with follow-up visits up to six months. The goal is to see if this approach is safe and can help the brain rewire or repair after demyelinating episodes.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Closed Loop Trans-Auricular Vagus Nerve Stimulation System
- What this could lead to
- If it works, this could point toward a non-invasive way to improve motor function and possibly repair nerve damage in multiple sclerosis.
- What could go wrong
- This is an early feasibility study with only 70 participants, so results may not be conclusive. The intervention is experimental and may not provide benefit over sham stimulation.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Clinical Translational Research Center at CU Anschutz
Aurora, Colorado, 80010, United States
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