Cure My Disease

Don't miss your cure!

 Log in / Sign up

Which wound closure method heals a burst abdomen faster?

NCT ID NCT07797868

Disease control Sponsor: Assiut University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 01, 2026 · Last updated Sep 02, 2026 · Updated 1 time

Summary

This trial tests two approaches for treating burst abdomen, a serious complication where the abdominal wound reopens after surgery. Half the participants will receive vacuum-assisted closure, a device that applies gentle suction to the wound. The other half will undergo graduated primary skin closure, where stitches are tightened gradually. Researchers will measure how long each method takes to fully close the wound, along with hospital stay, infection rates, and pain.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Vacuum-assisted closure (VAC) therapy and graduated primary skin closure are the two procedures being compared.
What this could lead to
If one method proves faster or safer, it could become the preferred standard for treating burst abdomen, reducing hospital stays and hernia risk.
What could go wrong
This is a small, early trial with only 50 participants, so results may not apply broadly. Both procedures carry risks like infection or pain, and the study may not show a clear winner.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 50 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Oct 2026

An estimate. Start dates often move.

Expected to finish

Nov 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult patients aged 18 years or older of either sex * Clinically confirmed complete (full-thickness) postoperative burst abdomen following a midline or paramedian laparotomy * Medically fit to tolerate bedside wound management/re-intervention (hemodynamically stable, not requiring vasopressor support) * Patient or legal guardian willing and able to provide written informed consent Exclusion Criteria: * Planned or pre-existing open abdomen (laparostomy) at the index operation * Presence of enterocutaneous or enteroatmospheric fistula at the wound site * Uncontrolled intra-abdominal sepsis or ongoing hemodynamic instability precluding safe wound management * Known hypersensitivity or allergy to polyurethane foam or adhesive drape materials used in VAC systems * Active malignancy with peritoneal carcinomatosis where wound closure is not a treatment priority * Pregnancy * Refusal to participate or to be randomized

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Abdominal wound dehiscence are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Incisional Hernia Postoperative Complications Surgical Wound Dehiscence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Abdominal wound dehiscence Burst abdomen Surgical wound dehiscence

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  2. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

More trials for these conditions

Other studies related to the condition(s) this trial covers.