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Can suction therapy heal infected leg wounds faster?

NCT ID NCT07795489

Disease control Sponsor: Sargodha Medical College Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 31, 2026 · Last updated Sep 04, 2026 · Updated 3 times

Summary

This trial tests whether vacuum-assisted closure (VAC), a device that applies gentle suction to a wound, helps infected lower-limb wounds heal faster than standard dressings. Researchers will enroll 90 adults with infected leg wounds and randomly assign half to receive VAC and half to receive conventional dressings. They will measure wound size after one week and track how long it takes for complete healing, aiming to see which method leads to better outcomes.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Vacuum-assisted closure (VAC) therapy, a device that uses negative pressure to help wounds heal
What this could lead to
If VAC works better, it could speed up healing of infected lower-limb wounds, reduce the need for amputation, and shorten hospital stays.
What could go wrong
This is a small, single-center trial, and results may not apply to all patients. VAC therapy can be uncomfortable and carries risks like infection or tissue damage.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

90 people

The number who actually took part.

Started

Jul 2025

Finished

Aug 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 40 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult population aged 18 - 40 years. * Gender;both male and female. * Patients having infected wound of lower limb (as per operational definition). Exclusion Criteria: * \> Recurrent cases (on medical record) * Patients with metabolic diseases, taking steroids, with peripheral vascular disease, cancer. * Patients with complications such as septic shock, diabetic ketoacidosis, or kidney injuries (on medical record) * Patients whose vitals were unstable (on clinical examination and medical record) * Patients with any evidence of underlying bone osteomyelitis and malignancy (on medical record).

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Conditions

The condition(s) this trial relates to.

Wound Infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Diabetic wound Infected wound

Contacts and locations

Locations

  • Dr Faisal Masood teaching Hospital Sargodha

    Sargodha, Punjab Province, 40100, Pakistan

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