New hope to stop dangerous transplant complication

NCT ID NCT04572815

Summary

This trial is testing if a drug called ustekinumab can prevent a serious complication called graft-versus-host disease (GVHD) after a stem cell transplant for blood cancers. About 116 patients will receive either the drug or a placebo alongside their standard transplant care. The goal is to see if calming the immune system with this drug can stop the donor cells from attacking the patient's body.

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Contacts and locations

Locations

  • City of Hope Comprehensive Cancer Center,

    Duarte, California, 91010, United States

  • Fred Hutch/University of Washington Cancer Consortium

    Seattle, Washington, 98109, United States

  • H. Lee Moffitt Cancer Center & Research Institute

    Tampa, Florida, 33612, United States

  • Roswell Park Cancer Institute

    Buffalo, New York, 14263, United States

Conditions

Explore the condition pages connected to this study.