Can a single drug stop transplant rejection? new trial hopes to find out
NCT ID NCT04572815
First seen Dec 12, 2025 · Last updated May 05, 2026 · Updated 26 times
Summary
This study tests whether the drug ustekinumab can prevent acute graft-versus-host disease (GVHD) in adults receiving a stem cell transplant from an unrelated donor for blood cancers. GVHD occurs when donor cells attack the patient's body. Ustekinumab aims to calm the immune system to reduce this risk. The trial involves 116 participants and compares ustekinumab to a placebo.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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City of Hope Comprehensive Cancer Center,
Duarte, California, 91010, United States
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Fred Hutch/University of Washington Cancer Consortium
Seattle, Washington, 98109, United States
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H. Lee Moffitt Cancer Center & Research Institute
Tampa, Florida, 33612, United States
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Roswell Park Cancer Institute
Buffalo, New York, 14263, United States
Conditions
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