Sleep better, age better? study tests urolithin a and fisetin

NCT ID NCT06990256

Ongoing Symptom relief Sponsor: Huazhong University of Science and Technology Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Aug 11, 2026 · Updated 3 times

Summary

This study is testing whether two dietary supplements, urolithin A and fisetin, can improve sleep quality and reduce signs of aging in middle-aged and older adults. Eighty participants aged 30-75 with poor sleep will take one of the supplements, a combination, or a placebo daily for 12 weeks. Researchers will measure sleep using questionnaires and overnight monitoring, and check aging markers like inflammation and DNA changes in blood and stool samples.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Urolithin A and Fisetin (dietary supplements)
What this could lead to: If it works, this could point toward a simple nutritional supplement strategy to improve sleep quality and slow certain aspects of aging.
What could go wrong: This is a small, early-phase trial with only 80 participants, so results may not apply to everyone. The supplements may show no benefit over placebo, and long-term effects are unknown.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

sleep disorder sleep-wake disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AGING SLEEP DISORDER

Contacts and locations

Locations

Wuchang Hospital Affiliated to Wuhan University of Science and Technology

Wuhan, Hubei, 430000, China

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