Can urine sodium levels guide better heart failure treatment?

NCT ID NCT07263035

Recruiting now Symptom relief Sponsor: Lakeland Regional Health Systems, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether adjusting the dose of a diuretic (water pill) based on urine sodium levels can improve outcomes for people hospitalized with acute heart failure. Researchers will compare two urine sodium targets against standard care in 600 adults. The goal is to see if this approach increases fluid removal, shortens hospital stays, and reduces readmissions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Furosemide (Lasix) intravenous solution
What this could lead to: If successful, this could lead to a more effective way to use existing diuretics to reduce hospital stays and readmissions for heart failure patients.
What could go wrong: This is a single-center trial, so results may not apply broadly. The approach is still experimental and may not improve outcomes over standard care.

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Conditions

The condition(s) this trial relates to.

congestive heart failure heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE HEART FAILURE (AHF) HEART FAILURE HEART FAILURE - NYHA II - IV HEART FAILURE ACUTE

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Lakeland Regional Hospital
RECRUITING

Lakeland, Florida, 33805, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

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