Urine biomarkers may spot kidney damage before standard tests do

NCT ID NCT07704242

First seen Jul 15, 2026 · Last updated Jul 16, 2026 · Updated 1 time

Summary

This observational study looks at whether two urine markers, NGAL and KIM-1, can detect early kidney injury in women undergoing gynecologic laparoscopic surgery. The surgery involves gas inflation and a head-down position that can stress the kidneys. Researchers will compare these markers in patients positioned at 30° versus 45° head-down tilt to see if they reveal damage before standard blood tests do.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could lead to a simple urine test to catch kidney damage earlier during laparoscopic surgeries, potentially preventing serious injury.
What could go wrong
This is a small observational study, so results may not apply to all patients or surgeries. The biomarkers may not prove reliable enough for routine use.

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Conditions

The condition(s) this trial relates to.

acute kidney injury Pneumoperitoneum

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Medipol Mega University Hospital

    Istanbul, Istanbul, 34214, Turkey (Türkiye)

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

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