Cure My Disease

Don't miss your cure!

 Log in / Sign up

Immediate scope procedure vs waiting: which eases kidney stone pain faster?

NCT ID NCT05715086

Symptom relief Sponsor: University of California, San Francisco Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 15, 2026 · Last updated Sep 16, 2026 · Updated 1 time

Summary

Researchers at the University of California, San Francisco are running a trial to compare two ways of managing a painful ureteral stone that brings people to the emergency department. One group receives ureteroscopy right away, a procedure that uses a scope to remove or break up the stone. The other group is observed first and has surgery later if needed. The trial measures pain and anxiety scores, plus how long patients stay in the hospital, to see which approach works better for adults with stones at least 5 millimeters wide.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
ureteroscopy, a procedure that uses a scope to find and remove or break up ureteral stones
What this could lead to
If immediate ureteroscopy works better, it could become the standard approach for patients who arrive at the emergency department with a painful obstructing stone.
What could go wrong
The trial may show no clear difference between the two approaches, or immediate surgery may carry risks such as infection or injury that outweigh the benefits for some patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 100 people

The number the study aims to enrol. It can still change while the study runs.

Started

Sep 2023

Expected to finish

Dec 2030

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Presenting to the Emergency Department (ED) * Adult (\> 18 yo) * ≥5mm ureteral stone diagnosed on CT scan * Presence of symptoms (pain, nausea, vomiting, hematuria) Exclusion Criteria: * Strict indication for stent * Stone burden not amenable to Ureteroscopy (URS) * Dirty urine analysis (UA) or positive urine culture (UCx) * Transplant kidney * Presence of conduit * Comorbidities not optimized for surgery * Strong preference for surgery or observation

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Ureteral stone are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

ureterolithiasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Ureteral stone

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • University of California, San Francisco

    TERMINATED

    San Francisco, California, 94143, United States

  • University of Colorado

    RECRUITING

    Aurora, Colorado, 80045, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.