Could training one limb at a time boost heart health better than both?

NCT ID NCT07751445

First seen Aug 07, 2026 · Last updated Aug 07, 2026

Summary

This study tests whether doing strength exercises one limb at a time (unilateral) or both limbs together (bilateral) makes a bigger difference in heart rate variability, muscle strength, and daily function for adults with high blood pressure. Adults aged 40-75 with hypertension will be randomly placed into one of three groups: unilateral training, bilateral training, or a control group. Both training groups will do supervised resistance exercises twice a week for 12 weeks. The goal is to see which approach better supports heart health and physical performance, potentially guiding safer and more personalized exercise advice.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Unilateral or bilateral resistance training (supervised exercise program)
What this could lead to
If one training style proves better, it could lead to more effective exercise prescriptions for managing blood pressure and improving heart health in people with hypertension.
What could go wrong
This is a small, early-stage trial, so results may not apply to everyone. Exercise is generally safe, but there is a risk of injury or strain, and the benefits may not be dramatic.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Munzur University Faculty of Health Sciences

    RECRUITING

    Tunceli, Turkey (Türkiye)

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