Tiny nerve study could unlock secrets of blood pressure
NCT ID NCT03513770
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-stage study looks at how the body's nervous system controls blood pressure when veins are stretched. Researchers will use a blood pressure cuff to temporarily block blood flow in the arm and measure nerve activity in the leg, along with vein size using an MRI. They will also test whether a common painkiller (ketorolac) changes these responses. The study involves 18 healthy adults aged 21-35 and aims to better understand basic body functions, not to treat any disease.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ketorolac tromethamine (an intravenous NSAID)
What this could lead to
If successful, this study could help scientists better understand how blood pressure is regulated, potentially pointing toward new treatments for conditions like fainting or low blood pressure.
What could go wrong
This is a very small, early-phase study with only 18 healthy volunteers, so results may not apply to patients with medical conditions. The intervention is short-term and not intended to treat any disease.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Penn State Milton S. Hershey Medical Center
RECRUITINGHershey, Pennsylvania, 17033, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••