Tiny nerve study could unlock secrets of blood pressure
NCT ID NCT03513770
First seen Jun 27, 2026 · Last updated Jul 10, 2026 · Updated 2 times
Summary
This early-stage study looks at how the body's nervous system controls blood pressure when veins are stretched. Researchers will use a blood pressure cuff to temporarily block blood flow in the arm and measure nerve activity in the leg, along with vein size using an MRI. They will also test whether a common painkiller (ketorolac) changes these responses. The study involves 18 healthy adults aged 21-35 and aims to better understand basic body functions, not to treat any disease.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- ketorolac tromethamine (an intravenous NSAID)
- What this could lead to
- If successful, this study could help scientists better understand how blood pressure is regulated, potentially pointing toward new treatments for conditions like fainting or low blood pressure.
- What could go wrong
- This is a very small, early-phase study with only 18 healthy volunteers, so results may not apply to patients with medical conditions. The intervention is short-term and not intended to treat any disease.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for BLOOD PRESSURE are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Penn State Milton S. Hershey Medical Center
RECRUITINGHershey, Pennsylvania, 17033, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Spinal implant may tackle pain and blood pressure together
- Wrist-Worn blood pressure monitor put to the test against gold standard
- AI and a pulse oximeter may predict dangerous blood pressure swings in spinal cord injury
- Could a simple cuff replace needles for blood pressure monitoring?
- Daily vitamin pills may sharpen teen minds and strengthen bones, large trial tests
- Brain-Safe bypass: smart monitor aims to personalize blood pressure during heart surgery