Scientists probe the hidden types of severe childhood asthma

NCT ID NCT04680117

Completed Knowledge-focused Sponsor: Assistance Publique - Hôpitaux de Paris Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study looked at 54 children with severe asthma to better understand the different biological features (endotypes) of the disease. Researchers collected blood, saliva, and nasal samples, along with lung samples from bronchoscopies, to analyze immune cells, metabolism, and microbes. The goal was to identify distinct subtypes of severe asthma in children aged 0 to 12 years, which could eventually lead to more tailored treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this research could help doctors better understand different types of severe asthma in children, leading to more personalized treatments in the future.
What could go wrong: This is an observational study, not a treatment trial. It aims to gather information, so there is no direct benefit to participants. The findings may not immediately change clinical practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

asthma chronic asthma follicular lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SEVERE ASTHMA

Contacts and locations

Locations

Name: Hôpital Necker-Enfants Malades

Paris, 75015, France

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