New study seeks to unlock the secrets of language learning in kids
NCT ID NCT04558541
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how children with developmental language disorder (DLD) learn patterns in speech and grammar. Researchers want to see if a general difficulty with learning sequences links problems with sounds and sentence structure. The goal is to create better, earlier tests and therapies. About 400 children, ages 4 to 8, with and without language disorders, will take part.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 400 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Aug 2022
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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4 to 8 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Because clinical precision is required, 4- to 8-year-olds will complete a large test battery. * All children (TD, DLD, DLD + SSD, SSD) will score above 75 on the Nonverbal Scale of the Kaufman Assessment Battery for Children (KABC-II), which is above the Diagnostic and Statistical Manual cut-off for intellectual disability, even considering the standard error of measurement. * Hearing will be within normal limits * Oral structures will be within normal limits (Robbins \& Klee, 1987). * The Childhood Autism Rating Scale (Schopler et al., 2010) and parent report, will be used to rule out autism. Children with DLD will meet standard criteria. * Children with DLD will score below the cutoff of 87 on the Structured Photographic Expressive Language Test-P2 (SPELT-P2; Dawson et al., 2005) that has demonstrated high diagnostic accuracy for DLD. * Children with DLD will perform below 80% in their spontaneous production of finite verb morphemes. * Performance on a nonword repetition task will also support DLD status. Scores below 70% for total phonemes correct across all nonword lengths are greater than 1 SD below the mean for typical children. * Speech production skills will be measured via the Goldman-Fristoe Test of Articulation-3 (GFTA-3; Goldman \& Fristoe, 2015) and the inconsistency subtest of the Diagnostic Evaluation of Articulation and Phonology (DEAP, Dodd, et al., 2006). Many 4- to 6-year-old children with DLD are expected to perform below expected levels on the GFTA-3; for this study half of the children with DLD will show performance below expected levels and half above a standard score of 85. Children with SSD will show impaired performance on the GFTA-3, but typical performance on grammatically weighted language measures (SPELT-P2 and finite verb morphemes). The DEAP serves as a standardized measure of segmental inconsistency and will provide a post hoc analysis that may be related to sequence pattern variability. Performance on the following measures will serve as covariates and will not be exclusionary for DLD or SSD: * Peabody Picture Vocabulary Test, 4th ed (Dunn \& Dunn, 1997) * Expressive Vocabulary Test, 2nd ed (Williams, 1997) * Verbal and nonverbal memory span. * Because of the emphasis on English phonological and morpho-syntactic patterns, all participants will be monolingual English learners or report dominant exposure to English from infancy. Exposure to other languages will be documented. Exclusion Criteria for all participants: * Hearing impairment * Intellectual impairment * Autism * Significant motor impairment. Typical participants will be excluded if they show: -Histories of developmental, speech, language, or hearing disorders.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Boys Town National Research Hospital
RECRUITINGOmaha, Nebraska, 68131, United States
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University of Arizona
RECRUITINGTucson, Arizona, 85721, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- A new online approach may help children master the tricky /r/ sound
- Can Parents' everyday talk rewire young brains to boost language?
- AI speech coach boosts Kids' articulation in hybrid therapy trial
- Can quizzing help kids with language delays learn new words?