Scientists probe why insulin fails to open blood vessels in obesity

NCT ID NCT03318094

First seen Mar 11, 2026 · Last updated Apr 30, 2026 · Updated 5 times

Summary

This study looks at why insulin doesn't widen blood vessels as it should in people with obesity and insulin resistance. Researchers think overactive nerve signals may be blocking insulin's effect. They will test this by temporarily blocking those nerve signals in the forearm and measuring changes in blood flow and glucose uptake. The goal is to better understand the problem, not to provide a treatment.

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Contacts and locations

Locations

  • Autonomic Dysfunction Center

    Nashville, Tennessee, 37232, United States

Conditions

Explore the condition pages connected to this study.