Stem cells may unlock mystery of chemo-related heart damage

NCT ID NCT03199300

Ongoing Knowledge-focused Sponsor: University Medical Center Groningen Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study uses stem cells made from patients' own cells to understand why some people develop severe heart or lung side effects from certain chemotherapy drugs. Researchers will compare cells from patients who had extreme toxicity to those who did not. The goal is to uncover the root causes of these side effects and improve long-term care for cancer survivors.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help doctors predict which patients are at risk for heart damage from chemotherapy, leading to safer, personalized cancer treatments.
What could go wrong: This is a small, early-stage study with only 20 participants, so results may not apply to everyone. It is observational and does not test a new treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cancer cardiovascular disorder chemotherapy-induced toxicity Neoplasms, Second Primary secondary malignant neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CANCER, TREATMENT-RELATED CARDIOVASCULAR MORBIDITY TOXICITY DUE TO CHEMOTHERAPY

Contacts and locations

Locations

University Medical Center Groningen

Groningen, 9713 GZ, Netherlands

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