Rare disease mystery: scientists watch AMN progress in hopes of finding a cure
NCT ID NCT05008874
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study followed 65 adult men with a rare inherited nerve disease called AMN (a form of spastic paraplegia) to understand how their symptoms change over time. Researchers collected data on walking ability and quality of life. The goal was to fill gaps in knowledge about the disease's progression, which could help design better treatments in the future. However, the study was stopped early, so results may be limited.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this study could provide crucial data to help design future treatments for AMN, a rare and poorly understood disease.
What could go wrong
This is an observational study, not a treatment trial. It was terminated early, so the data may be incomplete and not lead to clear conclusions.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for AMN are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Amsterdam UMC
Amsterdam, Netherlands
-
Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
-
Stanford Neuroscience Health Center
Stanford, California, 94304, United States
-
University of Leipzig Medical Center
Leipzig, Germany
-
University of Utah
Salt Lake City, Utah, 84112, United States
-
Weill Medical College of Cornell University
New York, New York, 10065, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.