Rare disease mystery: scientists watch AMN progress in hopes of finding a cure
NCT ID NCT05008874
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study followed 65 adult men with a rare inherited nerve disease called AMN (a form of spastic paraplegia) to understand how their symptoms change over time. Researchers collected data on walking ability and quality of life. The goal was to fill gaps in knowledge about the disease's progression, which could help design better treatments in the future. However, the study was stopped early, so results may be limited.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this study could provide crucial data to help design future treatments for AMN, a rare and poorly understood disease.
- What could go wrong
- This is an observational study, not a treatment trial. It was terminated early, so the data may be incomplete and not lead to clear conclusions.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Amsterdam UMC
Amsterdam, Netherlands
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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Stanford Neuroscience Health Center
Stanford, California, 94304, United States
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University of Leipzig Medical Center
Leipzig, Germany
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University of Utah
Salt Lake City, Utah, 84112, United States
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Weill Medical College of Cornell University
New York, New York, 10065, United States
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