Cord blood cells take on scleroderma in new trial
NCT ID NCT04356287
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether infusions of stem cells from donated umbilical cords are safe and can help people with systemic sclerosis, a rare disease that causes skin hardening and organ damage. 18 adults with severe disease will receive either the stem cells or a placebo. Researchers will check for side effects and measure changes in skin thickness over 12 months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- umbilical cord-derived mesenchymal stromal cells (stem cells)
- What this could lead to
- If it works, this could point toward a new treatment to control systemic sclerosis and reduce skin thickening.
- What could go wrong
- This is a very early, small trial with only 18 people. The treatment may not work or could cause side effects. It is not a cure.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for MESENCHYMAL STEM CELLS are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Sir Mortimer B. Davis Jewish General Hospital
RECRUITINGMontreal, Quebec, H3T 1E2, Canada
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can stem cell mist heal lungs damaged by cancer immunotherapy?
- Could stem cell exosomes recolor white patches in vitiligo?
- Stem cells infused to aid stroke recovery
- Experimental drug HZN-825 tested for rare scleroderma lung and skin damage
- Muscle stem cell study ends early — but may pave way for future treatments
- Stem cells may boost islet transplants for pancreatitis patients