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A quick ultrasound of the thigh may reveal frailty in older ICU patients

NCT ID NCT06523348

Diagnosis Sponsor: University Hospital, Toulouse Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
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Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

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Expanded access (paused)
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Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

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Status unknown
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First seen Aug 31, 2026 · Last updated Sep 01, 2026 · Updated 1 time

Summary

Researchers in Toulouse are testing whether a bedside ultrasound of the quadriceps muscle can diagnose frailty in adults aged 65 and older admitted to intensive care. They will compare the ultrasound measurements with the standard Clinical Frailty Scale, which relies on a clinician's judgment. The study involves 70 participants and follows them for three months to see if the ultrasound predicts outcomes. If the method works, it could offer a more objective, quick way to assess frailty in critically ill older adults.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Ultrasound measurement of the quadriceps muscle thickness
What this could lead to
If it works, a simple bedside ultrasound could help doctors identify frail older patients in intensive care more objectively, potentially guiding better care decisions.
What could go wrong
This is a small, single-center diagnostic study, so results may not apply broadly. Ultrasound measurements can vary between operators, and the test may not match the clinical scale in all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

70 people

The number who actually took part.

Started

Aug 2024

Finished

Jun 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Any patient aged 65 or over admitted to intensive care or the emergency department who meets the eligibility criteria

Ages

65 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * patient aged 65 or over * admitted to intensive care or the outpatient department for less than 24 hours * with an abdominal CT scan less than 30 days prior to admission OR who are scheduled for an scheduled for a routine abdomino-pelvic CT scan within the first 24 hours of admission Exclusion Criteria: * Neuromuscular disease * Lower limb amputation * Paraplegia \> 24 hours before admission * Clearly infected, burnt or lacerated ultrasound site. * Guardianship or curatorship * Opposition of the patient or his/her trusted support person or relative * Abdominal and pelvic CT scan not available in the previous month and not scheduled within the first 24 hours of treatment

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Conditions

The condition(s) this trial relates to.

Frailty

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Frailty Intensive care unit syndrome

Contacts and locations

Locations

  • UHToulouse

    Toulouse, France

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