Sound waves against addiction: ultrasound trial targets alcohol cravings

NCT ID NCT06518785

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether low-intensity focused ultrasound (LIFU) can safely calm overactive brain areas linked to alcohol cravings. Twenty-five adults with alcohol use disorder will receive LIFU while researchers monitor side effects and measure brain activity changes with fMRI. The goal is to see if this non-invasive technique can reduce the brain's response to alcohol cues.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Low-Intensity Focused Ultrasound (LIFU)

What this could lead to

If successful, this could point toward a non-invasive brain stimulation treatment to help people with alcohol use disorder reduce cravings and regain control.

What could go wrong

This is a very early, small safety study with only 25 participants, so results may not apply widely. The treatment is still experimental and may not effectively change drinking behavior.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

alcohol abuse substance-related disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of California, San Francisco

    RECRUITING

    San Francisco, California, 94143, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••