Super-Fine ultrasound could spare melanoma patients a second surgery
NCT ID NCT04702854
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This trial investigates whether a new, ultra-high-frequency ultrasound device can accurately measure the depth of skin melanomas before surgery. Currently, doctors must remove the tumor, measure its depth under a microscope, and then often perform a second surgery to remove more tissue or check lymph nodes. If this ultrasound method proves reliable, it could allow doctors to plan and perform the complete treatment in one operation. The study will enroll 60 adults with suspected melanoma and compare the ultrasound measurements to the standard lab analysis.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Ultrasound Biomicroscopy (VEVO MD device)
What this could lead to
If successful, this imaging method could allow doctors to determine melanoma depth before the first surgery, enabling complete removal and lymph node analysis in a single procedure.
What could go wrong
This is a small, early-stage study with only 60 participants. Previous high-frequency ultrasound attempts were not accurate enough, and this new approach may also fail to match the gold-standard histological measurement.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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CHU de Nice
Nice, France