Prostate cancer radiation cut to just 5 sessions in new trial

NCT ID NCT00911118

Completed Disease control Sponsor: Memorial Sloan Kettering Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase I trial tested a new type of radiation therapy for low- and intermediate-risk prostate cancer that delivers a higher dose each day, completing treatment in just 5 sessions over 2 weeks instead of the usual 45-48. The study enrolled 120 participants to check the safety and side effects of this approach. Researchers also looked at PSA levels, biopsy results, and sexual function after treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: ultra-hypofractionated image-guided intensity-modulated radiotherapy
What this could lead to: If successful, this could offer a shorter, more convenient radiation treatment for prostate cancer, reducing the number of sessions from 45-48 to just 5 over 2 weeks.
What could go wrong: This is an early phase I trial focused on safety, so it's not yet proven to be effective. The higher daily radiation dose may increase side effects, and results may not apply to all prostate cancer patients.

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Conditions

The condition(s) this trial relates to.

adenocarcinoma prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ADENOCARCINOMA PROSTATE CANCER

Contacts and locations

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Locations

Memorial Sloan Kettering Cancer Center

New York, New York, 10065, United States
Memorial Sloan Kettering Cancer Center @ Suffolk

Commack, New York, 11725, United States
Memorial Sloan Kettering Cancer Center@Phelps

Sleepy Hollow, New York, United States
Memorial Sloan Kettering Nassau

Uniondale, New York, 11553, United States
Memorial Sloan Kettering West Harrison

Harrison, New York, 10604, United States
Memorial Sloan Kettering at Mercy Medical Center

Rockville Centre, New York, United States
Montefiore Medical Center

The Bronx, New York, 10467, United States

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