New CT scanner aims to replace invasive heart tests for High-Risk patients
NCT ID NCT04272060
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares a new ultra-high-resolution CT scanner (UHR-CT) to the standard invasive coronary angiography for detecting significant blockages in the heart's arteries. It focuses on patients with severe calcium buildup or stents, where regular CT scans often fall short. The goal is to see if the UHR-CT can accurately identify which patients need further treatment without the risks of an invasive procedure.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Ultra-high-resolution CT scanner
What this could lead to
If successful, this could offer a noninvasive alternative to cardiac catheterization for diagnosing coronary artery disease in patients with severe calcification or stents.
What could go wrong
This is a small, early-phase study with only 50 patients, so results may not apply broadly. The CT may still miss some blockages compared to the invasive gold standard.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Hospital Israelita Albert Einstein
São Paulo, Brazil
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Iwate Medical University
Morioka, Japan
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Johns Hopkins Hospital
Baltimore, Maryland, 21287, United States