Bile acid pill may turbocharge liver regrowth after transplant

NCT ID NCT07664020

Not yet recruiting Disease control Sponsor: Institute of Liver and Biliary Sciences, India Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This trial tests whether ursodeoxycholic acid (UDCA), a bile acid supplement, can speed up liver regeneration in adults receiving a living-donor liver transplant. Participants take UDCA or a placebo starting at least 10 days before surgery and continuing for 10 days after. Researchers measure liver volume regrowth, liver function, and biomarkers to see if UDCA helps the liver recover faster.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: ursodeoxycholic acid (UDCA)
What this could lead to: If UDCA speeds liver regrowth, it could help transplant recipients recover faster and reduce early complications.
What could go wrong: This is a small, early-phase trial with only 130 participants. UDCA may not improve regeneration, and some people may have side effects like digestive upset.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CHRONIC LIVER DISEASE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

liver disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC LIVER DISEASE

Contacts and locations

Locations

ILBS

New Delhi, National Capital Territory of Delhi, 110070, India

More trials for these conditions

Other studies related to the condition(s) this trial covers.