Olive oil nutrient and creatine team up to fight fatigue in new study

NCT ID NCT06883292

Completed Symptom relief Sponsor: Applied Science & Performance Institute Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This completed trial tested whether tyrosol (a compound found in olive oil) and creatine, alone or together, can improve endurance, strength, and fatigue resistance in healthy adults. Fifty active men and women aged 18–50 took supplements or a placebo for about 4 weeks. They completed a series of physical and cognitive tests before and after supplementation to measure any changes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: tyrosol and creatine monohydrate
What this could lead to: If it works, this could point toward a simple supplement combination to improve physical performance and recovery in active people.
What could go wrong: This is a small, completed trial in healthy adults, not a patient population. Results may not apply to others, and supplements often show limited real-world benefits.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cognitive disorder tyrosinemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COGNITION CREATINE ENDURANCE PERFORMANCE TYROSOL

Contacts and locations

Locations

Applied Science & Performance Institute

Tampa, Florida, 33634, United States

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