Massive typhoid vaccine trial aims to curb fever in india
NCT ID NCT05500482
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This large study tested a typhoid conjugate vaccine called TyphiBEV in over 72,000 people aged 1 to 30 years in Vellore, India. The goal was to see if the vaccine reduces the number of confirmed typhoid fever cases in vaccinated communities compared to unvaccinated ones. The trial is now complete, and results will show how well the vaccine works in a real-world, high-burden setting.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Typhoid conjugate vaccine (TyphiBEV)
What this could lead to
If successful, this vaccine could significantly reduce typhoid fever in high-burden areas, potentially saving lives and lowering healthcare costs.
What could go wrong
This is a completed Phase 4 trial, so results are available, but real-world effectiveness may vary. The vaccine may not work equally in all populations or settings.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Christian Medical College Vellore
Vellore, Tamil Nadu, 632002, India