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Double injection may double pain relief after lung surgery

NCT ID NCT07700823

Symptom relief Sponsor: Shiyou Wei Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
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Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

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Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
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Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
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Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 14, 2026 · Last updated Jul 15, 2026 · Updated 1 time

Summary

This study tests whether giving a nerve block at two rib levels instead of one can better control pain after video-assisted thoracoscopic surgery for lung cancer. Eighty-eight adults scheduled for lung surgery will receive either a standard single-point block or a two-point block, both using the same total amount of numbing medicine. Researchers will measure pain scores, opioid use, and recovery quality to see if the two-point approach improves outcomes.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
a nerve block procedure using local anesthetic injected at two rib levels (3rd and 5th) compared to the standard single injection at the 5th rib
What this could lead to
If the two-point block proves better, it could become a new standard for pain control after thoracoscopic lung surgery, reducing opioid needs and speeding recovery.
What could go wrong
This is a small, single-center observational study, not a randomized trial, so results may be influenced by patient selection. The two-point block may also carry a slightly higher risk of complications like bleeding or pneumothorax.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 88 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Aug 2026

An estimate. Start dates often move.

Expected to finish

Sep 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

This single-center, prospective observational cohort study is conducted at Shanghai Pulmonary Hospital, Tongji University School of Medicine, China. It enrolls adults aged 18-85 years with ASA physical status I-III, scheduled for elective unilateral video-assisted thoracoscopic surgery and planned for ultrasound-guided serratus anterior plane block as routine perioperative analgesia.Eligible participants will be consecutively enrolled after written informed consent. Patients are naturally assigned to two cohorts based on the block regimen selected by the attending anesthesiologist in standard clinical practice, with a target total sample size of 88 (\~44 per cohort). No study-initiated randomization or treatment intervention is applied; all clinical management follows institutional routine protocols.

Ages

18 to 85 years

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Aged 18 to 85 years at enrollment, regardless of sex * American Society of Anesthesiologists (ASA) physical status grade I to III * Scheduled for elective unilateral video-assisted thoracoscopic surgery * Planned to receive ultrasound-guided SAPB for routine perioperative analgesia * Able to understand study procedures and provide written informed consent Exclusion Criteria: * Local infection or skin lesion at the block puncture site * Known hypersensitivity or allergy to amide local anesthetics * Preexisting sensory abnormality in the chest wall surgical area * Chronic opioid use for \> 3 months, history of chronic pain syndrome, or history of opioid abuse * Severe coagulopathy (international normalized ratio \> 1.5 or platelet count \< 80 × 10⁹/L) * Cognitive impairment or inability to cooperate with postoperative pain assessment * Refusal to provide written informed consent

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Conditions

The condition(s) this trial relates to.

lung cancer lung neoplasm Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Lung cancer Pain Serratus anterior plane block Video-assisted thoracoscopic surgery

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