New insulin system under Real-World watch: will it keep diabetes patients safer?
NCT ID NCT07356089
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is tracking 1,875 people with type 1 diabetes (ages 6 and up) who are already using the Twiist automated insulin delivery system. Researchers are monitoring for severe low blood sugar events, diabetic ketoacidosis, and hospitalizations related to the device. The goal is to see how well the system works in everyday life, outside of a controlled clinic setting.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Twiist Automated Insulin Delivery System (insulin pump, CGM sensor, and algorithm)
- What this could lead to
- If successful, this study could confirm that the Twiist system is safe and effective for daily use, helping people with type 1 diabetes manage their blood sugar more easily.
- What could go wrong
- This is an observational study, not a controlled trial, so it cannot prove the device causes or prevents outcomes. Risks include severe hypoglycemia, diabetic ketoacidosis, and device-related side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for TYPE 1 DIABETES (T1D) are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Jaeb Center for Health Research
RECRUITINGTampa, Florida, 33647, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can Open-Source insulin systems match commercial ones without meal announcements?
- A glucose Monitor's second chance: can it tame type 1 diabetes in High-Risk teens?
- Could a smart pen take the guesswork out of insulin dosing?
- AI takes the wheel: could a smart algorithm optimize insulin pumps from home?
- Can a common diabetes pill make insulin therapy safer and more effective for type 1 diabetes?
- Could a metabolic modulator help people with type 1 diabetes use insulin better?