New shot could simplify schizophrenia treatment

NCT ID NCT06253546

First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time

Summary

This phase 1 trial tests a single injection of TV-44749, an extended-release form of olanzapine, in Chinese adults with stable schizophrenia. The study aims to check safety, tolerability, and how the drug moves through the body. Participants receive one of three doses of the injection or continue oral olanzapine for comparison.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

TV-44749 (extended-release injectable olanzapine)

What this could lead to

If successful, this could provide a longer-lasting treatment option for schizophrenia, potentially reducing the need for daily pills.

What could go wrong

This is an early phase 1 trial with only 24 participants, so safety and effectiveness are not yet established. Side effects may occur, and results may not apply to broader populations.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Teva Investigational Site 88046

    Shanghai, 200030, China

  • Teva Investigational Site 88047

    Guangzhou, 510370, China

  • Teva Investigational Site 88048

    Beijing, 100191, China

  • Teva Investigational Site 88049

    Beijing, 100088, China

  • Teva Investigational Site 88050

    Wuhan, 430022, China

  • Teva Investigational Site 88056

    Xi'an, 710061, China