New imaging technique may forecast lymphoma treatment response

NCT ID NCT07657494

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study explores whether advanced PET/CT scans using special tracers can predict how well patients with aggressive lymphoma will respond to treatment and their long-term outlook. Researchers will inject two types of imaging agents—FAPI and Grazytracer—to visualize the tumor's environment, including cancer-associated fibroblasts and immune cell activity. The goal is to develop models that help doctors identify patients at risk of relapse or resistance early on.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Al18F-NOTA-FAPI and Al18F-NOTA-grazytracer/68Ga-grazytracer (imaging tracers)
What this could lead to
If successful, these imaging methods could help doctors predict which patients will respond to treatment and who might relapse, enabling more personalized care.
What could go wrong
This is an early-stage observational study with only 94 participants, so results may not apply broadly. The imaging tracers are experimental and not yet proven to improve outcomes.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Cancer Center/Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College

    RECRUITING

    Beijing, Chao Yang, 100021, China

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