Simple injection may boost skin graft success in head and neck cancer patients
NCT ID NCT04967391
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 3 trial tests whether injecting a fluid (tumescence) before harvesting a skin graft helps the graft heal better after head and neck cancer surgery. About 58 adults having reconstructive surgery will be randomly assigned to receive tumescence or standard care. The main goal is to see if the technique improves graft take and reduces complications like infection or extra clinic visits.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
tumescence (fluid injection)
What this could lead to
If it works, this technique could improve skin graft healing, reduce infections, and cut down on extra clinic visits after head and neck cancer surgery.
What could go wrong
This is a small, single-center trial (58 people) testing a technique already standard in burn care. Results may not apply to all patients or settings.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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UC Davis Health
Sacramento, California, 95817, United States