New cocktail aims to boost brain repair after stroke
NCT ID NCT07283159
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether adding a protein from human urine (human urinary kallidinogenase) to the standard clot-busting drug tenecteplase helps people recover better after an acute ischemic stroke. The trial will enroll 200 adults who arrive at the hospital within 4.5 hours of stroke onset. The goal is to see if the combination improves functional outcomes without raising the risk of bleeding.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Tenecteplase and human urinary kallidinogenase (a protein from human urine that may help blood flow and reduce inflammation)
- What this could lead to
- If it works, this combination could become a new standard treatment to improve neurological recovery after acute ischemic stroke without increasing bleeding risk.
- What could go wrong
- This is an early phase 2 trial with only 200 participants, so results may not apply to all stroke patients. The added benefit of the second drug is unproven, and there is always a risk of side effects like bleeding.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Department of Neurology, General Hospital of Northern Theater Command
RECRUITINGShenyang, 110016, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Zapping the brain to restore swallowing after stroke?
- Can Brain-Triggered stimulation reawaken arms after stroke?
- Can lifestyle choices after a stroke extend life and prevent a second one?
- Can Clot-Removing devices improve stroke recovery?
- A tiny neck implant could catch Stroke-Causing clots before they reach the brain
- Can virtual games retrain the brain to restore balance?