Gene therapy cocktail aims to wipe out bladder cancer before surgery

NCT ID NCT07332351

First seen Jan 12, 2026 · Last updated Apr 29, 2026 · Updated 16 times

Summary

This study tests whether adding a gene therapy (nadofaragene firadenovec) to standard chemotherapy and immunotherapy before bladder removal surgery can improve outcomes for people with muscle-invasive bladder cancer. About 33 adults will receive the combination treatment, then have their bladder removed to check if the cancer is gone. The goal is to see if this approach leads to a complete response, meaning no cancer remains in the removed bladder.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fred Hutch/University of Washington Cancer Consortium

    Seattle, Washington, 98109, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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