Personalized dosing may reduce transplant side effects in kids

NCT ID NCT06861257

Recruiting now Knowledge-focused Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how the chemotherapy drug treosulfan is processed in children getting a stem cell transplant. The goal is to find the right dose for each child to reduce side effects and improve outcomes. Researchers will measure drug levels in the blood and track how patients respond. The study includes 70 children with cancer or other serious blood disorders.

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Conditions

The condition(s) this trial relates to.

cancer disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MALIGNANT DISORDERS NON MALIGNANT DISORDERS PEDIATRIC HEMATOPOIETIC STEM CELL TRANSPLANTATION

Contacts and locations

Locations

AOU Città della Salute e della Scienza Di Torino, SC Oncoematologia Pediatrica e Centro Trapianti
RECRUITING

Torino, Torino, 10126, Italy
Azienda Ospedaliera di Padova, Oncoematologia Pediatrica
RECRUITING

Padova, Padova, 35128, Italy
Fondazione IRCCS Policlinico San Matteo, S.C. Ematologia 2 - Oncoematologia Pediatrica
RECRUITING

Pavia, Pavia, 27100, Italy
Fondazione IRCCS San Gerardo dei Tintori - Clinica Pediatrica
RECRUITING

Monza, Monza-brianza, 20900, Italy
IRCCS Istituto Giannina Gaslini, U.O.S.D. Centro Trapianto di Midollo Osseo
RECRUITING

Genova, Genova, 16147, Italy
IRCCS Materno Infantile "Burlo Garofolo", SC Oncoematologia Pediatrica e SS Trapianto Di Midollo
RECRUITING

Trieste, Trieste, 34137, Italy
Ospedale Donna Bambino Azienda Ospedaliera Universitaria Integrata, U.O.C. Oncoematologia Pediatrica
RECRUITING

Verona, VR, 37126, Italy
Ospedale San Raffaele, U.O. Immunoematologia Pediatrica
RECRUITING

Milan, Milano, 20132, Italy
Ospedali Civili, Presidio Ospedale Dei Bambini, Oncoematologia Pediatrica e TMO
RECRUITING

Brescia, Brescia, 25123, Italy
Policlinico Sant'Orsola Malpighi, Clinica Pediatrica Oncologia Ed Ematologia Pediatrica "Lalla Seràgnoli"
RECRUITING

Bologna, bOLOGNA, 40138, Italy

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