Gum treatment may cool artery inflammation after heart attack
NCT ID NCT04046237
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tests whether treating severe gum disease can reduce inflammation in the arteries of people who have recently had a heart attack. 210 participants will be randomly assigned to receive either intensive periodontal treatment or standard dental care. The main goal is to see if the treatment lowers inflammation in the carotid arteries, measured by PET scans at the start and after 12 months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Periodontal treatment (deep cleaning, root scaling, antiseptic irrigation)
What this could lead to
If it works, this could show that treating gum disease lowers artery inflammation, potentially reducing the risk of future heart attacks.
What could go wrong
This is an early-stage study focused on a biomarker (inflammation on PET scans), not on actual heart attack rates. The treatment is intensive and may not be practical for all patients.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for ACUTE MYOCARDIAL INFARCTION are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Hôpital Bichat, AP-HP
RECRUITINGParis, France
Contact Phone: •••-•••-•••• Email: •••••@•••••