Brain tissue bank could unlock secrets of recovery after head trauma
NCT ID NCT07683169
First seen Jul 06, 2026 · Last updated Jul 07, 2026 · Updated 1 time
Summary
This study collects and stores brain tissue from adults who have had a traumatic brain injury and require surgery to remove a bruise on the brain. Researchers will analyze the tissue to understand the molecular and cellular processes involved in brain damage and repair. The goal is to build a resource for future studies that may lead to better treatments for traumatic brain injury.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this research could uncover new targets for therapies that help the brain heal after injury.
- What could go wrong
- This is an observational tissue collection study, not a treatment trial. It may not directly lead to new therapies, and findings may take years to translate into clinical practice.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 500 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Oct 2024
- Expected to finish
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Oct 2044
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adult subjects
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged ≥18 years. * Diagnosis of traumatic brain injury (TBI). * Admission to the intensive care unit. * Clinical indication for neurosurgical evacuation of a cerebral contusion. * Written informed consent to participate to the study. Exclusion Criteria: * Coagulation disorders or other contraindications to the planned neurosurgical procedure.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Asst Papa Giovanni Xxiii
RECRUITINGBergamo, Italy
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Fondazione IRCCS San Gerardo dei Tintori
RECRUITINGMonza, Italy
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- MRI tracer could expose hidden brain energy crisis after head injury
- Blood and brain scans may expose invisible injury after head trauma
- Can a handheld scanner find brain bleeds faster on the battlefield?
- A quick eye ultrasound might spot brain pressure without a CT scan
- A new approach to taming Post-TBI fatigue: can group therapy delivered online make a difference?