New study aims to improve blood test accuracy for transgender patients

NCT ID NCT04478760

Completed Knowledge-focused Sponsor: King's College Hospital NHS Trust Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 2 times

Summary

This study will determine the normal reference intervals for 27 common blood tests in transgender adults who have been on stable hormone therapy for at least a year. Currently, standard reference ranges are based on sex assigned at birth, which may not be accurate for transgender individuals. By recruiting 250 healthy transgender participants, researchers hope to provide doctors with better tools to interpret lab results and detect disease earlier.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could provide doctors with accurate reference ranges for common blood tests in transgender people on hormone therapy, leading to faster and more accurate disease detection.
What could go wrong: This is an observational study, not a treatment trial. It only establishes reference intervals and does not test any new therapy. Results may not apply to all transgender individuals or those on different hormone regimens.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HORMONE REPLACEMENT THERAPY REFERENCE VALUES TRANSGENDER PERSONS

Contacts and locations

Locations

Caldecot Centre, King's College Hospital, 15-22 Caldecot Road

London, SE5 9RS, United Kingdom

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