New trial aims to find best drug to stop bleeding in High-Risk C-Sections

NCT ID NCT07423156

Not yet recruiting Disease control Sponsor: Allama Iqbal Medical College Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two drugs—tranexamic acid and vasopressin—to see which works better at reducing blood loss during planned C-sections in women with placenta previa, a condition where the placenta covers the cervix. 58 women will be randomly assigned to receive one of the drugs. The goal is to find a safer way to prevent severe bleeding and reduce the need for blood transfusions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Tranexamic acid and vasopressin
What this could lead to: If this trial shows one drug is better, it could lead to a standard treatment to reduce dangerous bleeding during C-sections for women with placenta previa.
What could go wrong: This is a small, early-phase trial with only 58 participants, so results may not apply to all patients. Both drugs have risks, and the study hasn't started yet.

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Conditions

The condition(s) this trial relates to.

diabetes insipidus placenta praevia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PLACENTA PREVIA

Contacts and locations

Locations

Jinnah Hospital

Lahore, Punjab Province, +92, Pakistan

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